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Kgotlholo e tona/Bolwetsi jwa mafatlha

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Tuberculosis
Maina a mangweKoch's disease,[1] phthisis, phthisis pulmonalis, consumption
Chest X-ray of a person with advanced tuberculosis: Infection in both lungs is marked by white arrow-heads, and the formation of a cavity is marked by black arrows.
SpecialtyInfectious disease, pulmonology
DikaiChronic cough, fever, cough with bloody mucus, weight loss[2]
CausesMycobacterium tuberculosis[2]
Risk factorsSmoking, HIV/AIDS[2]
Diagnostic methodCXR, culture, tuberculin skin test[2]
Differential diagnosisPneumonia, histoplasmosis, sarcoidosis, coccidioidomycosis[3]
PreventionScreening those at high risk, treatment of those infected, vaccination with bacillus Calmette-Guérin (BCG)[4][5][6]
TreatmentAntibiotics[2]
Frequency25% of people (latent TB)[7]
Deaths1.5 million (2018)[8]

Bolwetse jwa mafatlha ( TB ) ke bolwetse jo bo tshelanwang jo gantsi bo bakiwang ke mogare waMycobacterium tuberculosis ( MTB ).[2] Bolwetse jwa mafatlha ka kakaretso bo ama mafatlha, mme bo ka ama gape le dikarolo tse dingwe tsa mmele.[2] Bontsi jwa Meg are ga e ga e bontshe dikai dipe,mme mo lebakeng leo e itsege jaaka bolwetse jwa mafatlha jo bo fitlhegileng.[2] Palo e ka tshwarang 10% ya megare tse di fitlhegileng di tswelela go nna bolwetse jo bo matlhagatlhaga jo, fa bo tlogelwa bo sa alafiwe, bo bolayang mo e ka nnang Sephatlo sa ba ba amegang.[2] Dikai tsa tlwaelo tsa TB tse di matlhagatlhaga ke go gotlhola mo go sa foleng mo go nang le mamina a a nang le madi, letshoroma, go fufula bosigo, le go fokotsega ga boima jwa mmele.[2] E ne e bidiwa " tiriso " mo dusting ka ntlha ya go fokotsa boima jwa mmele.[9] Tshwaetso ya dirwe tse dingwe e ka baka dikai tse di farologaneng.[10]

Bolwetse jwa mafatlha bo anamisiwa go tswa mo mothong yo mongwe go ya kwa go yo mongwe ka mowa fa batho ba ba nang le TB e e matlhagatlhaga mo mafatlheng a bona ba gotlhola, ba kgwa mathe, ba bua, kgotsa ba ethimola.[2][11] Batho ba ba nang le TB e e fitlhegileng ga ba anamise bolwetse jono.[2] Megare e e matlhagatlhaga e tlhagelela gantsi mo bathong ba ba nang le HIV/AIDS le mo go ba ba gogang.[2] Temogo ya TB e e matlhagatlhaga e ikaegile ka maranta be a X-ray ya mafatlha, mmogo le tlhatlhobo ya maekerosekopo le setso sa diedi tsa mmele.[12] Go tlhatlhoba TB e e fitlhegileng go ikaegile ka teko ya letlalo ya tuberculin (TST) kgotsa diteko tsa madi.[12]

Thibelo ya TB e akaretsa go tlhatlhoba ba ba mo kotsing e kgolo, go lemoga le go alafa dikgetse go sa le gale, le go enta ka moento wa bacillus Calmette-Guérin (BCG).[4][5][6] Ba ba mo kotsing e kgolo ba akaretsa batho ba ba nang le TB e e matlhagatlhaga mo malapeng, kwa tirong, le mo setšhabeng.[5] Kalafi e tlhoka tiriso ya dibolayamegare tse dintsi mo pakeng e telele.[2] Go gana dibolayamegare ke bothata jo bo golang ka dikelo tse di oketsegang tsa bolwetse jwa mafatlha jo bo sa alafegeng ka diokobatsi tse dintsi (MDR-TB) le bolwetse jwa mafatlha jo bo sa alafegeng thata ka melemo (XDR-TB).[2]

Go tloga ka ngwaga wa 2018 go akanngwa gore kotara e le nngwe ya baagi ba lefatshe ba na le tshwaetsego e e fitlhegileng ya TB.[7] Megare e mesha e diragala mo go bokana ka 1% ya baagi ngwaga le ngwaga.[13] Ka ngwaga wa 2018, go ne go na le dikgetse di feta dimilione di le 10 tsa TB e e dirang e e neng ya felela ka 1.5. dintsho di le dimilione di le le some. Se se dira gore e nne selo sa ntlha se se bakang dintsho ka ntlha ya bolwetse jo bo tshelanwang.[14] Go tloga ka ngwaga we 2018, bontsi jwa dikgetse tsa TB di diragetse kwa dikgaolong tsa Borwa-Botlhaba jwa Asia (44%), Aforika (24%) le Pacific Bophirima (18%), mme go feta 50% ya dikgetse di ne tsa lemogiwa mo mafatsheng a robabobedi: India (27%), China (9%), Indonesia (8%), Philippines (6%), Pakistan (4%).[14] Palo ya dikgetsi tse diša ngwaga le ngwaga e fokotsegile fa e sale ka ngwaga wa dikete tse pedi.[2] Palo e e ka tshwarang 80% ya batho kwa mafatsheng ale mantis a Asia le Aforika ba tlhatlhobiwa ba na le mogare fa 5–10% ya batho ba baagi ba United States ba tlhatlhobiwa ka tlhatlhobo ya tuberculin.[15] Bolwetse jwa mafatlha bo ntse bo le teng mo bathong go tloga bogologolo tala.[16]

Ditshupiso

[fetola | Fetola Motswedi]
  1. "Tuberculosis (Concept Id: C0041296) - MedGen - NCBI". www.ncbi.nlm.nih.gov (in Sekgoa). Archived from the original on 16 November 2022. Retrieved 3 February 2025.
  2. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 "Tuberculosis (TB)". www.who.int (in Sekgoa). Archived from the original on 30 July 2020. Retrieved 2020-05-08.
  3. Ferri, Fred F. (2010). Ferri's differential diagnosis : a practical guide to the differential diagnosis of symptoms, signs, and clinical disorders (2nd ed.). Philadelphia, PA: Elsevier/Mosby. p. Chapter T. ISBN 978-0-323-07699-9.
  4. 1 2 Hawn TR, Day TA, Scriba TJ, Hatherill M, Hanekom WA, Evans TG, et al. (December 2014). "Tuberculosis vaccines and prevention of infection". Microbiology and Molecular Biology Reviews. 78 (4): 650–71. doi:10.1128/MMBR.00021-14. PMC 4248657. PMID 25428938.
  5. 1 2 3 Organization, World Health (2008). Implementing the WHO Stop TB Strategy: a handbook for national TB control programmes. Geneva: World Health Organization (WHO). p. 179. ISBN 978-92-4-154667-6. Archived from the original on 2 Seetebosigo 2021. Retrieved 28 Phukwi 2020.
  6. 1 2 Harris, Randall E. (2013). Epidemiology of chronic disease: global perspectives. Burlington, MA: Jones & Bartlett Learning. p. 682. ISBN 978-0-7637-8047-0. {{cite book}}: External link in |ref= (help)
  7. 1 2 "Tuberculosis (TB)". World Health Organization (WHO). 16 February 2018. Archived from the original on 19 September 2018. Retrieved 15 September 2018.
  8. "Global Tuberculosis Report" (PDF). WHO. WHO. 2019. Archived (PDF) from the original on 17 December 2019. Retrieved 24 March 2020.
  9. The Chambers Dictionary. New Delhi: Allied Chambers India Ltd. 1998. p. 352. ISBN 978-81-86062-25-8. Archived from the original on 6 Lwetse 2015.
  10. Adkinson, N Franklin; Bennett, John E; Douglas, Robert Gordon; Mandell, Gerald L (2010). Mandell, Douglas, and Bennett's principles and practice of infectious diseases (7th ed.). Philadelphia, PA: Churchill Livingstone/Elsevier. p. Chapter 250. ISBN 978-0-443-06839-3.
  11. "Basic TB Facts". Centers for Disease Control and Prevention (CDC). 13 Mopitlo 2012. Archived from the original on 6 Tlhakole 2016. Retrieved 11 Tlhakole 2016.
  12. 1 2 Konstantinos A (2010). "Testing for tuberculosis". Australian Prescriber. 33 (1): 12–18. doi:10.18773/austprescr.2010.005.
  13. "Tuberculosis". World Health Organization (WHO). 2002. Archived from the original on 17 Seetebosigo 2013.
  14. 1 2 "Global tuberculosis report". World Health Organization (WHO). Archived from the original on 30 October 2017. Retrieved 2017-11-09.
  15. Kumar, Vinay; Robbins, Stanley L. (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Elsevier. ISBN 978-1-4160-2973-1. OCLC 69672074.
  16. Lawn SD, Zumla AI (July 2011). "Tuberculosis". Lancet. 378 (9785): 57–72. doi:10.1016/S0140-6736(10)62173-3. PMID 21420161. Archived from the original on 27 August 2021. Retrieved 28 July 2020.